Effects of low-level laser therapy in skin autograft

a systematic review and meta-analysis protocol

Authors

  • Priscilla de Souza Porto
  • Fabiano Calixto Fortes de Arruda
  • Maria Alves Barbosa

Keywords:

Low-level Light Therapy, Skin Transplantation, Systematic Review

Abstract

Objective: To evaluate the effects of low-level laser therapy for the fixation of autologous skin grafts. Method: Systematic literature review and meta-analysis protocol. Studies will be selected according to the PICOS strategy (population, intervention, comparison, outcomes, study design). Research on the effects of using low-level laser therapy in the fixation of autologous skin grafts in humans or rats will be included, without date limits. Grey literature will be excluded. The EndNoteWeb software will be used for reference management. The tools of the Joana Briggs Institute for observational studies will be used to assess the risk of bias. By reading the article in full, the heterogeneity or homogeneity of the studies and the possibility or not of performing a meta-analysis will be verified.

References

Rajkumar J, Chandan N, Lio P, Shi V. The skin barrier and moisturization: function, disruption, and mechanisms of repair. Skin Paharmacol Physiol. 2023;36:174-85.

Rojer M, Fullard N, Costello L, Bradbury S, Markiewicz E, O’Reilly S et al. Bioengineering the microanatomy of human skin. J Anat. 2019;234(4): 438-55.

Radzikowska-Büchner E, Lopuszynska I, Flieger W, Tobiasz M, Maciejewski R, Flieger J. An overview of recent developments in the management of burn injuries. Int J Mol Sci. 2023;24(22):16357.

Kandiyali R, Thom H, Young AE, Greenwood R, Welton NJ. Cost-effectiveness and value of information analysis of a low-friction environment following skin graft in patients with burn injury. Pilot Feasibility Stud. 2020;31:6:8.

Spear M. Skin grafts: indications, applications and current research. IntechOpen; 2011. Available from: http://dx.doi.org/10.5772/892

Elseth A, Lopez ON. Wound grafts. StatPearls. 2025. Available from: https://www.ncbi.nlm.nih.gov/books/NBK564382/

Taha N, Daoud H, Malik T, Shettysowkoor J, Rahman S. The effects of low-level laser therapy on wound healing and pain management in skin wounds: a systematic review and meta-analysis. Cureus. 2024;16(10):e72542.

Castro TNS, Martignago CCS, Assis L, Alexandria FED, Rocha JCT, Parizotto NA, et al. Effects of photobiomodulation therapy in the integration of skin graft in rats. Lasers Med Sci. 2020;35(4):939-47.

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Published

2026-06-10

How to Cite

Porto, P. de S., Arruda, F. C. F. de, & Barbosa, M. A. (2026). Effects of low-level laser therapy in skin autograft: a systematic review and meta-analysis protocol. Revista De Divulgação Científica Sena Aires, 15(2), 102–107. Retrieved from https://rdcsa.emnuvens.com.br/revista/article/view/1227

Issue

Vol. 15 No. 2 (2026): REVISA

Section

Protocolo de Revisão

License

Copyright (c) 2026 Revista de Divulgação Científica Sena Aires

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

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